Mar 27, 2020
Try your hand at this medical mystery, which is followed by some
didactics on a fascinating disease which will hopefully make sense
of this inscrutable title.
Brought to you by GSK. Consider the long-term impact of
disease activity, flares and corticosteroid use on patients with
active SLE. Learn more now at treatfortodayandtomorrow.com
- Intro :22
- What to expect in each episode
:30
- The case: A 75-year-old man with Sjogren’s and MALT lymphoma
presents with recurrent cerebral infarcts of multiple territories
1:10
- Rheumatology is consulted 6:11
- Decreased sensation in toes occurs between strokes
7:14
- What’s going on with this patient?
8:36
- What additional labs can we perform?
9:36
- We spin the urine 11:10
- What kind of vasculitis are Sjogren’s and lymphoma associated
with? 12:22
- C3 and C4 had already been performed
13:00
- An overall picture of this patient
13:54
- What about the strokes? 14:19
- Should we do more imaging? 15:57
- At this point we can make a clinical decision
16:33
- Why make a decision so quickly vs. waiting for biopsy?
18:18
- Two things you must check before moving forward with a
cryoglobulinemic vasculitis 19:46
- Spoiler alert: The patient is doing really well
20:16
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patients with active SLE? Learn about a treatment option for your
patients at treatfortodayandtomorrow.com.
- What is cryoglobulinemic vasculitis?
21:00
- What are these immunoglobulins? There are three types of
cryoglobulins 22:55
- Usually driven by another identifiable disease
25:18
- What is making these immunoglobulins?
26:49
- We don’t know why these immunoglobulins behave this way
27:18
- How do you explain the kidneys?
28:28
- What’s occurring at the tissue level?
29:35
- How does type 1 present? 30:50
- Type 2 and type 3 31:12
- What other organ systems are involved?
33:11
- I hope you enjoyed this patient presentation
36:00
- What we’ll discuss in episodes 2 and 3
36:05
- Thanks for listening 38:03
**Coming soon from Healio, Unmasking COVID-19, a podcast hosted
by Gitanjali Pai, MD, infectious disease physician
at Memorial Hospital and Physicians’ Clinic in Stilwell, Oklahoma.
In this timely new show, Dr. Pai will explore COVID-19’s impact on
vulnerable patient populations by answering questions from experts
in various medical fields, including oncology, endocrinology and
rheumatology. To submit your question for Dr. Pai, email covid19podcast@healio.com.**
We’d love to hear from you! Send your comments/questions to
rheuminationspodcast@healio.com.
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Disclosure: Brown reports no relevant financial
disclosures.
References:
Fuentes A, et al. Current
Rheumatology Reports. 2019;21:60.
Silva F, et al. J Autoimmun.
2019;105:102313.